CASY counts not with a flat image, but with all three dimensions – Seeing Life as it is!
CASY also counts cells using Electronic Current Exclusion (ECE) and Pulse Field Analysis enable the accurate determination of viability without any influence by other variables such as staining or focusing. Viable cells are detected with full cell volume as the cell membrane provides a barrier for current, while dead cells with no membrane resistance have their nucleus detected.
CASY Working Principle
CASY measures the conductivity between 2 electrodes separated by a defined pore. Cells are suspended in CASYton, a defined buffer solution. Cells pass through the pore generate an electrical pulse that correlates with the volume of the cell with a GMP/GLP compliant precision allowing a maximum variation below ±2%.
With CASY cell counter, aggregates are not a problem. During counting, CASY uses mathematically correct volume-based aggregation correction. Mean volume and mean size even are calculated by determining how often a single cell fits into each aggregate detected. This is ideal when working with induced pluripotent stem cells (iPSC).
CASY Advantages
CASY’s cell counter and analyzer technology gives all-round information about your cells in a very short time. Your cell count, volume, aggregates and homogeneity are identified as well as any contaminations wit only 20-50 µl volume of your samples.
Generations of scientist have successfully trusted CASY cell counter and analyzer for decades. Its cell count and analysis performance are continuously improving as proven by its use in several thousands of publications globally and increasing each year. CASY cell counter and analyzer has been used for all kinds of cells. Whether you are analyzing PBMCs, T-cells, primary cells, bacteria, fungi or algae, CASY can do it. CASY can be equipped with up to 3 different capillaries, each optimized for a certain group of applications. Same time, switching between capillaries is easy and takes only minutes. No compromises or tradeoffs, whether you work with cell lines or primary cells, PBMCs or stem cells, yeast or bacteria. The easily exchangeable capillaries get you ready for the future.